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Testosterone Plus

Important Safety Information


Topical testosterone cream applied once every morning.

About this medicine

Bio identical testosterone plus cream treats symptoms of low libido, low energy, reduced motivation and vaginal dryness. Testosterone, estriol and progesterone are natural hormones made by the body. With increasing age, Estrogen declines. Estriol is a very weak Estrogen which is extremely safe and beneficial for vaginal health. Bioidentical hormones are made from the plant extract diosgenin and are identical in structure to the body’s own hormones

Your bio identical testosterone plus cream contains bio identical testosterone, bio identical progesterone and bio identical estriol in a hypoallergenic cream base. Your bio identical testosterone plus cream is pharmaceutical grade, compounded by the Specialist Pharmacy, the UK’s longest established compounding pharmacy regulated by and compliant with the GPhC and the MHRA. It contains only first-class GMP standard ingredients (GMP standard).

Main advantages of H+Y bio identical testosterone plus cream:

Our creams are pharmaceutical grade, which means they have maximum efficacy

Our creams use first-class pharmaceutical ingredients (GMP standard)

Our creams are free from fragrance, Gluten, Milk, Eggs, Fish, Treenut and Peanut

Convenient and easy to use

A single tube is sufficient for 3 months

How do I use this medicine?

Apply 1 pump of cream in the morning around the same time every day to the inside of the forearm, upper arm or inner thigh

Never apply to open sores, wounds, or irritated skin.

Completely clean and dry the skin. Squeeze 1 pump of the cream on the appropriate area. Using a circular motion, rub in the medication until it is absorbed and the area feels dry. Let the medication dry for a few minutes before getting dressed to prevent your clothes from wiping it off your skin.

Rotate the site of application to avoid skin irritation and saturation issues.

Wait half an hour after application before bathing or swimming to ensure the best absorption.

The cream will take 30 minutes to absorb so please refrain from applying anything further during this time. Should you need to apply sunscreen please do so 30 minutes after you’ve applied your hormone cream.

how quickly can i expect to see results

Wondering how quickly you can expect to see results? We’ve prepared an indicative timeline for you.

Months 0-3: Most women get relief of their symptoms in less than a week, for others it can take three months. If you’re not seeing improvement in symptoms by 2-3 months don’t panic, but before you re-order you need to liaise with a H+ You clinician as you may need an increased dose.

Months 3-6: Most women using testosterone plus cream will have already seen visible results.

Months 6-12: Most women will have significant improvement in their symptoms. The full results of treatment can be expected after 9-12 months. Most women need to continue testosterone plus cream for symptom improvement to be maintained. Some women find that after using their cream for some months or years, they can discontinue using the cream as their symptoms have cleared up.


Most women experience significant improvement by 6 months

Many women stay on treatment for a number of years - you can take it safely for a long time

In the event that your dosage needs to be changed, we're on this journey with you to help you manage changes.

- Every 3 months, before your next treatment arrives, you will be sent a follow-up questionnaire.


You are pregnant or breast feeding

You are currently on Hormone Replacement Therapy (HRT) or other hormone contraceptives

You are allergic to soy or yam

You have migraine with aura

You have acne, excessive hair growth (hirsutism) or frontal hair-loss

You have been diagnosed with breast, genital or liver cancer

You have porphyria

You have diabetes

You have undiagnosed vaginal bleeding

You have had a thromboembolism (blood clot)

You are taking medication for epilepsy (Carbamazepine, Lamotrigine, Perampanel, Phenobarbital, Phenytoin, Mysoline, Topiramate, Rufinamide)

You are taking medication for medication for HIV (Efavirenz, Nevirapine, Ritonavir)

You are taking medication for medication for narcolepsy (Modafanil)

You are taking medication for medication for TB (Rifabutin, Rifampicin)

You are a man (this medicine is for women)

You live outside the U.K

- You are under the age of 18

You partake in professional sports competitions

Are there any possible side effects?

Too much testosterone could cause the following side effects: 

  • Hyper-aggressiveness 

  • Excessive oiliness of skin 

  • Increased pimples/acne 

  • Increased hair growth on body, face &/or place of application 

  • Frontal hair loss from the head Too much estriol could cause the following side effects: Breast or nipple tenderness 

  • Pelvic cramps (with or without bleeding) 

  • Water retention (swollen fingers, legs &/or ankles) 

  • Hot flashes

Too much progesterone could cause the following side effects:

  • Drowsiness 

  • Waking up groggy &/or edgy 

  • Nausea 

  • Hot flashes (also a sign of too little progesterone) 

  • Feeling depressed 

  • Slight dizziness 

  • Leg discomfort/pain 

  • Water retention (also a sign of too little progesterone)

Stop using the medicine and talk to your H+Y clinician if you have any concerns.

How should I store the medicine? 

Store this medicine at room temperature. Keep this medicine out of the sight and reach of children.

Do not use this medicine after its beyond use date, which is printed on the dispensing label

Other important information 

Although bio identical testosterone plus cream helps many women, this medicine may not work for everyone. If you have no improvement in your symptoms after 6 months of use you should speak to your H + You clinician – it might be that a different dose is recommended or that you consider stopping treatment.

Our online consultation process should not replace your regular visits to your GP. Please keep your GP informed of any medicines you are taking.

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Pharmacy owner: The London Specialist Pharmacy Ltd (GPhC: 9010630)Address: Specialist Pharmacy, Londoneast-UK Business & Technical Park, Yew Tree Avenue, Dagenham, RM10 7FNSuperintendent Pharmacist: Rizvan Batha (GPhC: 2080291)Pharmacy Contact Information: - 020 7637 1055© 2023, Gluck International Limited, All Rights Reserved, is a company registered in England and Wales with the number 09753512. You-nique are trademarks of Hormones and You.